Monitor More, Clean Less.
In today’s fast-paced research and manufacturing environments, accurate pressure monitoring is essential for maintaining process control, ensuring product quality, and meeting regulatory standards. PendoTECH’s suite of monitors, available from Cole-Parmer, pairs seamlessly with single-use pressure and temperature sensors to deliver a flexible, accurate, and scalable solution for monitoring in fluid systems. These technologies support efficient scale-up and streamlined development workflows while reducing contamination risks, minimizing cleaning requirements, and simplifying validation.
Why Choose Single-Use Pressure and Temperature Sensors?
Single-use pressure and temperature sensors offer clear advantages over traditional reusable sensors in sterile and high-purity environments:
Reduced Risk of Cross-Contamination: Designed for single use, these sensors eliminate the need for cleaning and sterilization between batches.
Simplified Validation: Single-use components reduce cleaning validation requirements and support faster batch turnovers.
Scalability: Easily implemented in both pilot and production-scale systems.
Gamma-Compatible: Suitable for sterilization via gamma irradiation, ensuring integrity in aseptic conditions.
Cost-Effective: Minimizes the long-term costs associated with maintenance, calibration, and cleaning of reusable sensors.
PendoTECH’s single-use sensors are robust enough for repeated cleaning yet affordable for disposable applications, making them a reliable alternative to stainless steel pressure transducers. Each sensor is pretested for accuracy, manufactured in an ISO 9001-certified facility, and USP Class VI compliant, making them ideal for critical biopharmaceutical processes.
Overview of PendoTECH Monitors Available from Cole-Parmer
Cole-Parmer offers three PendoTECH monitor options, each designed for different use cases and levels of process integration:
Best For: Scalable lab or pilot plant applications requiring multi-point pressure monitoring with high accuracy and rugged, portable design.
Features:
Supports up to four pressure sensor inputs across different model options.
Compact and portable footprint, ideal for easy movement and space-limited environments.
Output real-time pressure data to a PC, higher-level control system, or relay switch to enable interfacing with pumps and valves.
Best For: Multifunctional data integration and monitoring across pressure, flow, and analog sensor inputs for comprehensive bioprocess control.
Features:
Handles up to three single-use pressure sensors, 1 flowmeter input, and one 4-20 mA input across various models.
The 4-20mA input function is user configurable and can be used to read and display measurements from an external transmitter.
Output real-time monitoring of pressure, flow rate, and total flow volume to a PC or control system for efficient data collection.
Best For: Portable, on-the-go pressure measurements with high accuracy and fast display updates for quick checks of lab or pilot-scale setups.
Features:
Accepts one single-use pressure sensor.
Lightweight, handheld design with 14-hour battery life for on-the-go diagnostics..
View minimum and maximum pressure values at the touch of a button to monitor process fluctuations effectively.
How to Integrate Sensors and Monitors into Your Fluid System
Incorporating single-use sensors and monitors into your system is straightforward and highly adaptable:
Install Sensors Inline: Sensors can be installed at key monitoring points such as before and after filters, within bioreactor lines, or upstream pumps. Choose from various connection types including hose barb, Luer, and sanitary flange to suit your system configuration.
Connect To Monitors: Single-use sensors come with the required cables for direct connection to PendoTECH monitors. Alternatively, the PendoTECH Adapter Cable can be used to enable compatibility with third-party transmitters, control systems, or custom electronic circuits.
Interface With Control Systems: PressureMAT and PressureMAT Plus offer analog and digital outputs that can be integrated into your existing control system, PC, or fluid handling equipment.
Calibration and Validation: Sensors are pretested, eliminating calibration requirements and come with certificates, easing compliance with GMP and quality requirements.
Supporting Components for a Complete Monitoring System
A robust fluid handling system relies on more than just sensors. Cole-Parmer offers a wide selection of complementary components to create a complete, high-performing fluid handling system:
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Peristaltic Pumps: Gentle, pulse-free flow is ideal for cell culture, chromatography, and filtration applications. Look for pumps with ports compatible with PressureMAT outputs for seamless integration.
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Tubing: Choose gamma-stable, biocompatible tubing like TPE or silicone that matches your pressure requirements and sterilization needs.
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Fittings: Select fittings that properly mate with single-use sensor connections, such as sanitary or Luer interfaces, to ensure secure, leak-free integration. Quick-connect or aseptic options further support ease of use and system flexibility.
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Valves: Use manual or automated valves to regulate fluid flow and isolate system sections. PressureMAT monitors include relay outputs that can control valve actuation based on pressure readings, enabling automated response for improved process control.
Application Examples
Tangential Flow Filtration (TFF)
PendoTECH pressure monitors provide critical pressure readouts across the filter membrane. Monitoring transmembrane pressure (TMP) in real time helps optimize yield and prevent membrane fouling.
Chromatography
Pressure monitoring upstream and downstream of the column helps detect blockages, avoid over-pressurization, and improve column longevity. Continuous data logging supports process validation and ensures consistent separation performance.
Fill-Finish
The handheld DPG monitors are especially useful during fill-finish operations for quick validation of pressure across sterile filters. Their portability and fast response make them ideal for maintaining sterility and compliance in high-precision dosing applications.
Experience the Single-Use Advantage
PendoTECH’s monitors and single-use sensors offer a reliable, scalable, and contamination-free method for pressure monitoring in bioprocessing systems. With options for everything from research labs to fully automated production environments and supported by a full suite of fluid handling components from Cole-Parmer, these solutions simplify compliance, reduce risk, and improve process control.
Shop our full range of sensors and monitors and experience the convenience of this reliable, ready-to-use suite of integrated sensors and transmitters.
