The HG-400 MiniG® is small yet powerful tissue homogenizer and cell lyser. The adjustable clamp can handle sample vials from 2 mL to 50 mL or up to two deep-well microplates. Using the bead beating method, it is designed for rapid cell disruption, cell lysis, and tissue homogenization. Common applications for this model include DNA/RNA research and extraction, protein extraction, biofuel research, and pesticide residue extraction via the QuEChERS or SWeET method.

The HG-400 MiniG® is the perfect solution for labs looking for a compact yet high-performance tissue homogenizer and cell lyser. Designed for quick and efficient sample processing, this versatile system ensures fast and consistent extractions of nucleic acids, proteins, and other key molecules—all with minimal effort. It is equipped with an adjustable clamp that accommodates a full range of sample vials from 2 mL to 50 mL centrifuge tubes or up to two deep-well titer plates. It is specifically designed for rapid cell disruption, cell lysis and tissue homogenization through bead beating.

Typical applications include: tissue homogenization, DNA/RNA research and extraction, cell lysis, protein extraction, biofuel research, pesticide residue extraction using QuEChERS or the SweEt method.

Typical samples include: animal tissue, plant tissue, cell cultures, fruit, cannabis, seeds, yeast and bacteria.

The Cole-Parmer SamplePrep HG-400 MiniG® is designed for fast, reliable and efficient sample processing. The unit homogenizes cells and tissues in less than two minutes with powerful bead beating technology. The HG-400 works with a variety of sample types including seeds, stems, roots, leaves, and animal tissue.

The MiniG accommodates 2 mL to 50 mL centrifuge tubes or up to two deep-well titer plates. The adjustable clamp secures different vial sizes, ensuring flexibility for various applications. The easy to operate unit lets you load samples, set time and speed, and press start, and let the MiniG do the work.

Reliable and consistent results through the mechanical grinding process that eliminates the variability of manual grinding, making it ideal for high-throughput labs. The HG-400 MiniG works with or without buffer allowing for dry pulverization of plant tissue using grinding balls.

The vertical shaking motion delivers strong and uniform disruption. Its small footprint makes is easy to optimize lab space without sacrificing performance.

Effective September 2023, the Spex SamplePrep 1600 MiniG® has now been rebranded Cole-Parmer® SamplePrep under model number HG-400 MiniG®. All the same great features and specifications, just with a new and improved look.